Initializr is an HTML5 template generator which is based on HTML5Boilerplate, a powerful HTML5 template created by Paul Irish and Divya Manian. But do not expect you could configure template layout with several columns like you already have idea in your mind. This can only generate standard template with jQuery preloaded or old browsers like IE6 fix. At lease, you can use it to make your own design from this sample files. I hope it will add some more features soon.